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Enews Now
June 2018

Skin Barrier Mutations and Environmental Exposures Could Contribute to Food Allergy

In a novel animal study published in The Journal of Allergy and Clinical Immunology (JACI), researchers from Northwestern University Feinberg School of Medicine found that a combination of skin barrier mutations and environmental exposures may increase the rate of food allergy.

They found that in order for mice with skin barrier mutations to experience food allergy by means of skin sensitization, they need to be exposed to both food allergens and the fungal allergen Alternaria alternata or house dust mites. The article was covered in ScienceDaily, ScienceAlert and Today Online.

You can read the article, “Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation,” on the JACI’s website.